From 5 to 9 September 2022 in Florence, the first National School in Biophotonics and Artificial Intelligence – BPAI will be held. Biophotonics has applications ranging from chemical, biological, and microorganisms detection to biomedical imaging, generating highly complex information data. Artificial Intelligence (AI) is a disruptive technology with applications that permeate every field of knowledge. Paradigms such as Machine learning and Deep Learning are, in fact, able to discover hidden patterns in complex data and inspire new theoretical and experimental interpretations. The School was born precisely to explore the intersection between these two disciplines, creating a training course for developing AI applications in the field of Biophotonics. Moreover, the School aims to establish a virtuous training course for students and young researchers interested in applications at the border between the areas of Biophotonics and Artificial Intelligence, stimulating cross-fertilization between the two disciplines.